Tratamiento De COVID-19. Mitos Y Realidades Bajo La Perspectiva De La Investigación Clínica
[Treatment Of COVID-19. Myths And Realities Under The Perspective Of Clinical Research]
[Tratamiento De COVID-19. Mitos Y Realidades Bajo La Perspectiva De La Investigación Clínica [Treatment Of COVID-19. Myths And Realities Under The Perspective Of Clinical Research]]
Osvaldo Reyes1
1. Maternidad del Hospital Santo Tomás, Panamá Miembro del Sistema Nacional de Investigadores de Panamá Coordinación de investigaciones de la Maternidad del Hospital Santo Tomás;
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Resumen
La enfermedad producida por el SARS-CoV-2, conocida como COVID-19 (Coronavirus Disease 19), ha puesto el mundo en pausa y generado una respuesta masiva de la comunidad científica en todo el mundo, buscando una cura. Sin embargo, el deseo de obtener un tratamiento nunca debe ir por encima de la rigurosidad del proceso y, desafortunadamente, cada cierto tiempo aparece alguna noticia o publicación garantizando que cierto medicamento ha demostrado dar buenos resultados. Estas conclusiones, muchas veces, distan de la realidad, cuando se analiza la investigación que sustenta dicha aseveración. En este artículo reviso la evidencia disponible a la fecha sobre los potenciales tratamientos para el COVID-19, analizando las debilidades y fortalezas de cada uno y su potencial para el futuro.
Palabras claves: COVID-19, tratamiento, hidroxicloroquina,remdesivir, lopinavir, ritonavir, ivermectina, tocilizumab, suero convaleciente.
Abstract
The disease produced by SARS-CoV-2, known as COVID-19 (Coronavirus Disease 19), has put the world on hold and generated a massive response from the scientific community worldwide in search of a cure. However, the desire to obtain a treatment should never override the rigor of the process and unfortunately, every so often there is some news or publication guaranteeing that a certain drug has been shown to work. These conclusions are often far from the truth when the research supporting the claim is scrutinized. In this article, I review the evidence to date on potential treatments for COVID-19, analyzing the strengths and weaknesses of each and its potential for the future.
Key words: COVID-19, treatment, hydroxychloroquine, remdesivir, lopinavir, ritonavir, ivermectin, tocilizumab, convalescent sera.
Abstract
La enfermedad producida por el SARS-CoV-2, conocida como COVID-19 (Coronavirus Disease 19), ha puesto el mundo en pausa y generado una respuesta masiva de la comunidad científica en todo el mundo, buscando una cura. Sin embargo, el deseo de obtener un tratamiento nunca debe ir por encima de la rigurosidad del proceso y, desafortunadamente, cada cierto tiempo aparece alguna noticia o publicación garantizando que cierto medicamento ha demostrado dar buenos resultados. Estas conclusiones, muchas veces, distan de la realidad, cuando se analiza la investigación que sustenta dicha aseveración. En este artículo reviso la evidencia disponible a la fecha sobre los potenciales tratamientos para el COVID-19, analizando las debilidades y fortalezas de cada uno y su potencial para el futuro.
Palabras claves: COVID-19, tratamiento, hidroxicloroquina,remdesivir, lopinavir, ritonavir, ivermectina, tocilizumab, suero convaleciente.
Abstract
The disease produced by SARS-CoV-2, known as COVID-19 (Coronavirus Disease 19), has put the world on hold and generated a massive response from the scientific community worldwide in search of a cure. However, the desire to obtain a treatment should never override the rigor of the process and unfortunately, every so often there is some news or publication guaranteeing that a certain drug has been shown to work. These conclusions are often far from the truth when the research supporting the claim is scrutinized. In this article, I review the evidence to date on potential treatments for COVID-19, analyzing the strengths and weaknesses of each and its potential for the future.
Key words: COVID-19, treatment, hydroxychloroquine, remdesivir, lopinavir, ritonavir, ivermectin, tocilizumab, convalescent sera.
Citas
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